Amanda Randles

Alfred Winborne and Victoria Stover Mordecai Associate Professor of Biomedical Sciences

My research in biomedical simulation and high-performance computing focuses on the development of new computational tools that we use to provide insight into the localization and development of human diseases ranging from atherosclerosis to cancer. 

Appointments and Affiliations

  • Alfred Winborne and Victoria Stover Mordecai Associate Professor of Biomedical Sciences
  • Associate Professor of Biomedical Engineering
  • Assistant Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science
  • Assistant Professor of Computer Science
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: Wilkinson Building, Room No. 325, 534 Research Drive, Durham, NC 27708
  • Office Phone: +1 919 660 6962
  • Email Address:
  • Websites:


  • Ph.D. Harvard University, 2013

Research Interests

Biomedical simulation and high-performance computing

Awards, Honors, and Distinctions

  • Stansell Family Distinguished Research Award. Pratt School of Engineering. 2023
  • Pioneer Award. NIH. 2022
  • Fellow (NAI). National Academy of Inventors. 2021
  • Senior Member. National Academy of Inventors. 2019
  • IEEE-CS Technical Consortium on High Performance Computing (TCHPC) Award for Excellence for Early Career Researchers in High Performance Computing. IEEE. 2017
  • MIT TR35 Visionary. MIT TR35. 2017
  • Grace Murray Hopper Award. ACM. 2017
  • Ralph E. Powe Junior Faculty Enhancement Award. Oak Ridge Associated Universities. 2016
  • Best Paper, IEEE International Conference on Computational Science (ICCS) 2015. IEEE. 2015
  • Gordon Bell Finalist. ACM. 2015
  • Early Independence Award. NIH. 2014
  • U.S. Delegate . Heidelberg Laureate Forum. 2013
  • Lawrence Fellowship. Lawrence Livermore National Laboratory. 2013
  • Anita Borg Memorial Scholarship. Google. 2012
  • U.S. Delegate . Lindau Nobel Laureates and Students Meeting Dedicated to Physics. 2012
  • George Michael Memorial High Performance Computing Fellowship. ACM/IEEE. 2012
  • George Michael Memorial High Performance Computing Fellowship. ACM/IEEE. 2010
  • Gordon Bell Finalist. ACM. 2010
  • Computational Science Graduate Fellowship. Department of Energy. 2010
  • Graduate Research Fellowship. National Science Foundation. 2009

Courses Taught

  • EGR 393: Research Projects in Engineering
  • BME 792: Continuation of Graduate Independent Study
  • BME 791: Graduate Independent Study
  • BME 590L: Special Topics with Lab
  • BME 520L: Computational Foundations of Biomedical Simulation (GE, BB, MC)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 307: Transport Phenomena in Biological Systems (AC or GE, BB)

In the News

Representative Publications

  • Vardhan, Madhurima, Cyrus Tanade, S James Chen, Owais Mahmood, Jaidip Chakravartti, W Schuyler Jones, Andrew M. Kahn, et al. “Diagnostic Performance of Coronary Angiography Derived Computational Fractional Flow Reserve.” J Am Heart Assoc 13, no. 13 (July 2, 2024): e029941.
  • Seidel, Ed, Amanda Randles, Rick Arthur, Keren Bergman, Bill Carlson, Ewa Deelman, Ray Grout, Bruce Hendrickson, and Dan Reed. “2024 Advanced Scientific Computing Advisory Committee (ASCR) Facilities Subcommittee Recommendations.” USDOE Office of Science (SC), May 1, 2024.
  • Chidyagwai, Simbarashe G., Michael S. Kaplan, Christopher W. Jensen, James S. Chen, Reid C. Chamberlain, Kevin D. Hill, Piers C. A. Barker, Timothy C. Slesnick, and Amanda Randles. “Surgical Modulation of Pulmonary Artery Shear Stress: A Patient-Specific CFD Analysis of the Norwood Procedure.” Cardiovasc Eng Technol, March 8, 2024.
  • Geddes, Justen R., and Amanda Randles. “Optimizing Temporal Waveform Analysis: A Novel Pipeline for Efficient Characterization of Left Coronary Artery Velocity Profiles.” ArXiv, February 15, 2024.
  • Nan, Junyu, Sayan Roychowdhury, and Amanda Randles. “Investigating the Influence of Heterogeneity Within Cell Types on Microvessel Network Transport.” Cellular and Molecular Bioengineering 16, no. 5–6 (December 2023): 497–507.