Kewaunee Lecture: Laura Niklason, Ph.D., MD

May 6

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Monday, May 6, 2024

12:00 pm – 6:00 pm

Presenter: Laura Niklason, Ph.D., MD

Laura Niklason

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Kewaunee Flyer
Program

12:00pm-2:00pm Lunch and Poster session

2:00pm-2:30pm Networking Event and Award Counting

2:30pm-2:45pm CBTE Update & Awards - Tatiana Segura

2:45pm-3:15pm Faculty Talk #1 Andrew Jones

3:15pm-3:45pm Faculty Talk #2 Jatin Roper

3:45pm-4:15pm Faculty Talk #3 John Hickey

4:15pm-4:45pm Coffee break- Networking 

4:45pm-5:00pm Kewaunee Intro - George Truskey

5:00pm-6:00pm Kewaunee Lecture- Laura Niklason

 

"Bioengineering and Hopes for Changing Medicine"

Abstract:
Bioengineering at the device, cellular and molecular level is rapidly changing the practice and future of medicine.  New devices and diagnostic approaches are under constant and rapid development.  In addition, engineered cells that modulate the immune system, or deliver genetic payloads, are changing the way we treat cancer and genetic diseases.  Engineered tissues now are at the forefront of cellular engineering approaches:  to date, only a handful of engineered tissues have been approved by the FDA for clinical use.  Engineered tissues, or “human spare parts”, and the incipient next wave of revolutionary therapies, emerging from bioengineering, that will transform medicine.

In this lecture, advances in vascular engineering will be discussed.  Focus will be on the chronology of vascular tissue development, key challenges, and the tenacity that is required to bring a truly new therapy to the clinic.  Learnings and failures along the way from NIH-funded experimentation on the benchtop, to startup company product development, to FDA regulatory filings, will be described.  A willingness to attack important new problems and bring them to solution can be incredibly gratifying,  but it is not easy, since “all of the easy stuff has already been done.

 

Bio:

Dr. Niklason is the founder, President and CEO of Humacyte. Dr. Niklason founded Humacyte in 2005, while still a professor at Duke University. Humacyte is a regenerative medicine company of engineered blood vessels for dialysis access and for treatment of vascular trauma.   Dr. Niklason’s scientific career has focused primarily on regenerative strategies for cardiovascular and lung tissues.  She was inducted into the National Academy of Inventors in 2014, into the National Academy of Medicine in 2015, and inducted to the National Academy of Engineering in 2020.  She was also named (along with Bill Gates and Joe Biden) as one of 34 leaders who are changing healthcare by Fortune Magazine in 2017.  Niklason received PhD from the University of Chicago in Biophysics in 1988 and received her MD from the University of Michigan in 1991. Dr. Niklason completed her medical training in anesthesiology and critical care medicine at the Massachusetts General Hospital in 1996.  She was a professor at Duke University from 1998 – 2005, before moving to Yale University in 2005.  

The CBTE Symposium and Kewaunee Lecture will take place in Wilkinson Building.

Email Jessica Canning to register: Jessica.Canning@duke.edu