Evan Kurt

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Evan graduated with his B.S. in Chemical Engineering from Villanova University in 2017, followed by his M.S. in Biochemical Engineering in 2018 at Villanova. He is currently a PhD student in the Segura Lab, studying methods for gene therapy from hydrogel scaffolds.

Contact Information:

  • Email Address: evan.kurt@duke.edu

Research Interests:


Non-viral gene delivery from shred hydrogel microparticle scaffolds (sHMP-DNA) for tissue repair in ischemic stroke. Enhancing polyplex loading in hyaluronic acid hydrogels using caged polymer formulations. Characterizing transfection from scaffolds in 3D culture.


  • Truong, N. F., Kurt, E., Tahmizyan, N., Cai Lesher-Pérez, S., Chen, M., Darling, N. J., Xi, W. & Segura, T. Microporous annealed particle hydrogel stiffness, void space size, and adhesion properties impact cell proliferation, cell spreading, and gene transfer. Acta Biomater. (2019). doi:10.1016/J.ACTBIO.2019.02.054
  • Truong, N. F., Lesher-Pérez, S. C., Kurt, E. & Segura, T. Pathways Governing Polyethylenimine Polyplex Transfection in Microporous Annealed Particle Scaffolds. Bioconjug. Chem. acs.bioconjchem.8b00696 (2018). doi:10.1021/acs.bioconjchem.8b00696
  • Kurt, E. Ex Vivo T Cell Capture, Growth, Characterization, and Modification for CAR T Cell Therapy. ProQuest. (Villanova University, 2018). ISBN:9780355911169
  • Spivack, K., Muzzelo, C., Neely, C., Vanzelli, J., Kurt, E. & Elmer, J. Small Molecule Inhibition of the Innate Immune Response Increases Transgene Expression. bioRxiv 338707 (2018). doi:10.1101/338707


  • Non-viral Gene Delivery From Microporous Annealed Particle (MAP) Scaffolds; Nature Biomedical Engineering (May 2019)