Raluca Mihaela Gordan

Associate Professor in Biostatistics & Bioinformatics

Appointments and Affiliations

  • Associate Professor in Biostatistics & Bioinformatics
  • Associate Professor of Computer Science
  • Associate Professor of Cell Biology
  • Associate Professor in Molecular Genetics and Microbiology
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: 101 Science Drive, 2179 Ciemas, Durham, NC 27708
  • Office Phone: +1 919 684 9881
  • Email Address: raluca.gordan@duke.edu
  • Websites:

Education

  • Ph.D. Duke University, 2009

Awards, Honors, and Distinctions

  • Sloan Research Fellowship-Molecular Biology. Alfred P. Sloan Foundation. 2014

Courses Taught

  • UPGEN 778F: University Program in Genetics and Genomics Biological Solutions Module VI
  • UPGEN 778D: University Program in Genetics and Genomics Biological Solutions Module IV
  • COMPSCI 561: Computational Sequence Biology
  • COMPSCI 394: Research Independent Study
  • COMPSCI 393: Research Independent Study
  • CBB 700: Internship
  • CBB 591: Independent Study
  • CBB 561: Computational Sequence Biology

In the News

Representative Publications

  • Duan, Mingrui, Shenghan Song, Hana Wasserman, Po-Hsuen Lee, Ke Jian Liu, Raluca Gordân, Yi He, and Peng Mao. “High UV damage and low repair, but not cytosine deamination, stimulate mutation hotspots at ETS binding sites in melanoma.” Proc Natl Acad Sci U S A 121, no. 4 (January 23, 2024): e2310854121. https://doi.org/10.1073/pnas.2310854121.
  • Martin, Vincentius, Farica Zhuang, Yuning Zhang, Kyle Pinheiro, and Raluca Gordân. “High-throughput data and modeling reveal insights into the mechanisms of cooperative DNA-binding by transcription factor proteins.” Nucleic Acids Res 51, no. 21 (November 27, 2023): 11600–612. https://doi.org/10.1093/nar/gkad872.
  • Horton, Connor A., Amr M. Alexandari, Michael G. B. Hayes, Emil Marklund, Julia M. Schaepe, Arjun K. Aditham, Nilay Shah, et al. “Short tandem repeats bind transcription factors to tune eukaryotic gene expression.” Science 381, no. 6664 (September 22, 2023): eadd1250. https://doi.org/10.1126/science.add1250.
  • Glasscock, Cameron J., Robert Pecoraro, Ryan McHugh, Lindsey A. Doyle, Wei Chen, Olivier Boivin, Beau Lonnquist, et al. “Computational design of sequence-specific DNA-binding proteins.” BioRxiv, September 21, 2023. https://doi.org/10.1101/2023.09.20.558720.
  • Mielko, Zachery, Yuning Zhang, Harshit Sahay, Yiling Liu, Matthew A. Schaich, Brittani Schnable, Abigail M. Morrison, et al. “UV irradiation remodels the specificity landscape of transcription factors.” Proc Natl Acad Sci U S A 120, no. 11 (March 14, 2023): e2217422120. https://doi.org/10.1073/pnas.2217422120.