Christina Hofmann

Education:

Degree: BME in BME, 2015

Advisor: Mark Dewhirst, Greg Palmer, Mike Therien

Research Project: Delivery of Myoglobin Polymersomes Results in Tumor Hemorrhagic Necrosis and Enhanced Radiation Response

Research Interests:

PUBLICATIONS

  1. C. L. Hofmann, W. Qi, C. D. Landon, M.J. Therien, M. W. Dewhirst, P. P. Ghorochchian, G. M Palmer, Self-Assembling PEG-b-P(TMC-co-CL) Near-Infrared Emissive Polymersomes for Pharmacokinetics, Toxicity Anaylsis, and Noninvasive Imaging of Tumor Accumulation, Biomaterials (2015) In Preparation.
  2. B. L. Viglianti, M. W. Dewhirst, R. J. Boruta, J. Y. Park, C. D. Landon, A. N. Fontanella, J. Guo, A. Manzoor, C. L. Hofmann, G. M. Palmer. Systemic anti-tumour effects of local thermally sensitive liposome therapy, International Journal of Hyperthermia, 30(2014) 385-392. 
  3. M. W. Dewhirst, C. D. Landon, C. L Hofmann, P. R. Stauffer. Novel approaches to treatment of hepatocellular carcinoma and hepatic metastases using thermal ablation and thermosensitive liposomes, Surg Oncol Clinics N Am, 22 (2013): 545-561.

 

POSTERS

  1. C. L. Hofmann, J. Yewle, K. Ashcraft, M. J. Therien, M. W. Dewhirst, P. P. Ghoroghchian, G. M. Palmer, Tumor Delivery of Polymersome-Encapsulated Myoglobin Results in Rapid Intratumoral Hemorrhaging, 12th International Nanomedicine & Drug Delivery Symposium, Chapel Hill, NC (October 2014 - Best Abstract Award), 2nd Annual Duke Cancer Institute Scientific Retreat (November 2014), Durham, NC.
  2. Hofmann CL, Qi Wei, Landon CD, Therien MJ, Dewhirst MW, Palmer GM, In Vitro Drug Release and In Vivo Tumor Delivery of Near-Infrared Emissive Biodegradable Polymersomes Containing Poly(ethylene glycol) and Randomized Poly(trimethylen carbonate-co-caprolactone), Controlled Release Society Annual Meeting, Honolulu, Hawaii (July 2013).
  3. Hofmann CL, Qi Wei, Landon CD, Therien MJ, Dewhirst MW, Palmer GM, Pharmacokinetics and Tumor Accumulation of Near-Infrared Emissive Polymersomes Composed of Poly(ethylene glycol) and Random Poly(caprolactone-co-trimethylene carbonate), Fitzpatrick Institute for Photonics (FIP) 2013 Annual Meeting (March 2013 - 2nd Place Poster Award), Radiation Oncology & Imaging Program Annual Retreat (March 2013), Annual Kewaunee Lecture and Poster Session (April 2013), 1st Annual Duke Cancer Institute Scientific Retreat (May 2013), Durham, NC.
  4. Hofmann C.L, Qi W, Gill T, Ghoroghchian P, Palmer GM, Therien MJ, Dewhirst MW, Pharmacokinetics and Biodistribution Analysis Using Near-Infrared Emissive Polymersomes, American Association for Cancer Research Molecular Targets and Cancer Therapeutics Conference, San Francisco, CA (November 2011), Annual Kewaunee Lecture and Poster Session, Duke University (April 2012).
  5. Hofmann CL, Qi W, Gill T, Ghoroghchian P, Palmer GM, Therien MJ, Dewhirst MW, Polymersomes Containing Near-Infrared Emitting Porphyrins for In Vivo Imaging, Annual Kewaunee Lecture and Poster Session, Duke University (April 2011).
  6. Hofmann CL, Qi W, Gill T, Ghoroghchian P, Palmer GM, Therien MJ, Dewhirst MW, Polymersomes Containing Near-Infrared Emitting Poryphyrins, Radiation Oncology & Imaging Program Annual Retreat, Duke University (February 2011).

 

ORAL PRESENTATIONS

  1. Hofmann CL, Qi W, Gill T, Ghoroghchian P, Palmer GM, Therien MJ, Dewhirst MW, Pharmacokinetics and Biodistribution of NIR-Emissive Biodegradable Polymersomes: Accumulation within Mammary Carcinomas, World Biomaterials Congress, Chengdu, China (June 2012).
  2. C. L. Hofmann, J. Yewle, K. Ashcraft, M. J. Therien, M. W. Dewhirst, P. P. Dewhirst, G. M. Palmer, Tumor Delivery of Polymersome-Encapsulated Myoglobin Results in Rapid Intratumoral Hemorrhaging, 12th International Nanomedicine & Drug Delivery Symposium, Chapel Hill, NC.

 

AWARDS

  1. Best Abstract Award, 12th International Nanomedicine & Drug Delivery Symposium, Chapel Hill, NC.
  2. Center for Biomolecular and Tissue Engineering Service Award (2013)
  3. CRS Outstanding Preclinical Sciences & Animal Health Best Paper Ward (2013)
  4. 2nd Place Poster Award Fitzpatrick Institute for Photonics (FIP) Annual Meeting (2013)