Aravind Asokan

Asokan

Professor in Surgery

Synthetic Virology & Gene Therapy

Appointments and Affiliations

  • Professor in Surgery
  • Director of Gene Therapy
  • Professor of Biomedical Engineering
  • Professor of Molecular Genetics and Microbiology
  • Affiliate of the Duke Regeneration Center

Contact Information

Education

  • Ph.D. University of North Carolina - Chapel Hill, 2004

Research Interests

Virology
RNA Biology
Viral Engineering
RNA Engineering
Gene Therapy
Gene Editing
Gene Regulation
Regenerative Medicine

Courses Taught

  • BME 791: Graduate Independent Study
  • MGM 293: Research Independent Study I
  • MGM 593: Research Independent Study

Representative Publications

  • Havlik, LP; Das, A; Mietzsch, M; Oh, DK; Ark, J; McKenna, R; Agbandje-McKenna, M; Asokan, A, Receptor Switching in Newly Evolved Adeno-associated Viruses., J Virol, vol 95 no. 19 (2021) [10.1128/JVI.00587-21] [abs].
  • Gemberling, MP; Siklenka, K; Rodriguez, E; Tonn-Eisinger, KR; Barrera, A; Liu, F; Kantor, A; Li, L; Cigliola, V; Hazlett, MF; Williams, CA; Bartelt, LC; Madigan, VJ; Bodle, JC; Daniels, H; Rouse, DC; Hilton, IB; Asokan, A; Ciofani, M; Poss, KD; Reddy, TE; West, AE; Gersbach, CA, Transgenic mice for in vivo epigenome editing with CRISPR-based systems., Nat Methods, vol 18 no. 8 (2021), pp. 965-974 [10.1038/s41592-021-01207-2] [abs].
  • Gibson, RA; Lim, J-A; Choi, SJ; Flores, L; Clinton, L; Bali, D; Young, S; Asokan, A; Sun, B; Kishnani, PS, Characterization of liver GSD IX γ2 pathophysiology in a novel Phkg2-/- mouse model., Molecular Genetics and Metabolism, vol 133 no. 3 (2021), pp. 269-276 [10.1016/j.ymgme.2021.05.008] [abs].
  • Mitchell-Dick, A; Asokan, A, AAV-CNS matters turn from gray to white., Molecular Therapy : the Journal of the American Society of Gene Therapy, vol 29 no. 5 (2021), pp. 1659-1660 [10.1016/j.ymthe.2021.04.012] [abs].
  • Hunanyan, AS; Kantor, B; Puranam, RS; Elliott, C; McCall, A; Dhindsa, J; Pagadala, P; Wallace, K; Poe, J; Gunduz, T; Asokan, A; Koeberl, DD; ElMallah, MK; Mikati, MA, Adeno-Associated Virus-Mediated Gene Therapy in the Mashlool, Atp1a3Mashl/+, Mouse Model of Alternating Hemiplegia of Childhood., Hum Gene Ther, vol 32 no. 7-8 (2021), pp. 405-419 [10.1089/hum.2020.191] [abs].