Lingchong You

You

Professor of Biomedical Engineering

The You lab uses a combination of mathematical modeling, machine learning, and quantitative experiments to elucidate principles underlying the dynamics of microbial communities in time and space and to control these dynamics for applications in computation, engineering, and medicine.

Appointments and Affiliations

  • Professor of Biomedical Engineering
  • James L. Meriam Distinguished Professor of Biomedical Engineering
  • Associate Professor in Molecular Genetics and Microbiology
  • Professor in Molecular Genetics and Microbiology

Contact Information

Education

  • Ph.D. University of Wisconsin - Madison, 2002
  • M.S. University of Science and Technology of China (China), 1997
  • B.S.E. Chengdu University of Science and Technology (China), 1994

Research Interests

Quantitative biology, synthetic biology, machine learning, antibiotic resistance, microbiome

Awards, Honors, and Distinctions

  • Fellow. American Institute for Medical and Biological Engineering. 2019
  • Faculty Early Career Development (CAREER) Program. National Science Foundation. 2010
  • Young Professor Award. DuPont. 2008
  • Fellowships for Science and Engineering. David and Lucile Packard Foundation. 2006

Courses Taught

  • BIOLOGY 293-1: Research Independent Study
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 574: Modeling and Engineering Gene Circuits (GE, MC)
  • BME 791: Graduate Independent Study
  • CBB 574: Modeling and Engineering Gene Circuits (GE, MC)
  • EGR 393: Research Projects in Engineering
  • MGM 293: Research Independent Study I
  • MGM 593: Research Independent Study
  • PHARM 394: Research Independent Study

In the News

Representative Publications

  • Silver, A; You, L, A change of phase., Nature Chemical Biology (2022) [10.1038/s41589-022-01209-x] [abs].
  • Bethke, JH; Ma, HR; Tsoi, R; Cheng, L; Xiao, M; You, L, Vertical and horizontal gene transfer tradeoffs direct plasmid fitness., Molecular Systems Biology (2022) [10.15252/msb.202211300] [abs].
  • Wang, T; Weiss, A; Aqeel, A; Wu, F; Lopatkin, AJ; David, LA; You, L, Horizontal gene transfer enables programmable gene stability in synthetic microbiota., Nat Chem Biol, vol 18 no. 11 (2022), pp. 1245-1252 [10.1038/s41589-022-01114-3] [abs].
  • Şimşek, E; Yao, Y; Lee, D; You, L, Toward predictive engineering of gene circuits., Trends in Biotechnology (2022) [10.1016/j.tibtech.2022.11.001] [abs].
  • Lu, J; Tsoi, R; Luo, N; Ha, Y; Wang, S; Kwak, M; Baig, Y; Moiseyev, N; Tian, S; Zhang, A; Gong, NZ; You, L, Distributed information encoding and decoding using self-organized spatial patterns., Patterns (N Y), vol 3 no. 10 (2022) [10.1016/j.patter.2022.100590] [abs].