Kris Cameron Wood


Associate Professor of Pharmacology and Cancer Biology

Our laboratory uses genomic and pharmacological approaches to understand how tumor dependencies are shaped by cell intrinsic factors, environmental factors, and drug treatments during the dynamic process of tumor evolution. To learn more, please visit our laboratory website:

Appointments and Affiliations

  • Associate Professor of Pharmacology and Cancer Biology
  • Associate Professor of Cell Biology
  • Core Faculty in Innovation & Entrepreneurship
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location:
  • Office Phone:
  • Email Address:
  • Websites:


  • Ph.D. Massachusetts Institute of Technology, 2007
  • B.S. University of Kentucky, 2002

Awards, Honors, and Distinctions

    Courses Taught

    • CMB 710B: Cell & Molecular Biology Module II
    • CMB 710E: Cell & Molecular Biology Module V
    • MOLCAN 818: Molecular Mechanisms of Oncogenesis
    • PHARM 393: Research Independent Study
    • PHARM 394: Research Independent Study
    • PHARM 493: Research Independent Study
    • PHARM 494: Research Independent Study
    • PHARM 495: Research Independent Study
    • PHARM 818: Molecular Mechanisms of Oncogenesis
    • UPGEN 778A: University Program in Genetics and Genomics Biological Solutions Module I

    In the News

    Representative Publications

    • Mayro, B; Hoj, JP; Cerda-Smith, CG; Hutchinson, HM; Caminear, MW; Thrash, HL; Winter, PS; Wardell, SE; McDonnell, DP; Wu, C; Wood, KC; Pendergast, AM, ABL kinases regulate the stabilization of HIF-1α and MYC through CPSF1., Proc Natl Acad Sci U S A, vol 120 no. 16 (2023) [10.1073/pnas.2210418120] [abs].
    • Killarney, ST; Washart, R; Soderquist, RS; Hoj, JP; Lebhar, J; Lin, KH; Wood, KC, Executioner caspases restrict mitochondrial RNA-driven Type I IFN induction during chemotherapy-induced apoptosis., Nature Communications, vol 14 no. 1 (2023) [10.1038/s41467-023-37146-z] [abs].
    • Sarosiek, KA; Wood, KC, Endogenous and imposed determinants of apoptotic vulnerabilities in cancer, Trends in Cancer, vol 9 no. 2 (2023), pp. 96-110 [10.1016/j.trecan.2022.10.004] [abs].
    • Bassil, CF; Anderson, GR; Mayro, B; Askin, KN; Winter, PS; Gruber, S; Hall, TM; Hoj, JP; Cerda-Smith, C; Hutchinson, HM; Killarney, ST; Singleton, KR; Qin, L; Jubien-Girard, K; Favreau, C; Martin, AR; Robert, G; Benhida, R; Auberger, P; Pendergast, AM; Lonard, DM; Puissant, A; Wood, KC, MCB-613 exploits a collateral sensitivity in drug resistant EGFR -mutant non-small cell lung cancer through covalent inhibition of KEAP1., Biorxiv (2023) [10.1101/2023.01.17.524094] [abs].
    • Goodwin, CM; Waters, AM; Klomp, JE; Javaid, S; Bryant, KL; Stalnecker, CA; Drizyte-Miller, K; Papke, B; Yang, R; Amparo, AM; Ozkan-Dagliyan, I; Baldelli, E; Calvert, V; Pierobon, M; Sorrentino, JA; Beelen, AP; Bublitz, N; Lüthen, M; Wood, KC; Petricoin, EF; Sers, C; McRee, AJ; Cox, AD; Der, CJ, Combination Therapies with CDK4/6 Inhibitors to Treat KRAS-Mutant Pancreatic Cancer., Cancer Research, vol 83 no. 1 (2023), pp. 141-157 [10.1158/0008-5472.can-22-0391] [abs].