Sheridan earned a BS in Biomedical Engineering from the Georgia Institute of Technology in Atlanta, GA in 2015. She is a PhD student in Dr. Ravi Bellamkonda's lab.
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Immunotherapy, biomaterials, glioblastoma
Immunotherapy as a cancer treatment strategy has shown promise in manipulating the host immune system to perform anti-tumor functions. However, additional struggles exist in glioblastoma that diminishes immune cell infiltration and function in the immunosuppressive tumor microenvironment. Our strategy involves engineering biomaterials that reduce physiological barriers for intratumoral CAR T cell migration and modulate immune cell phenotype to produce a more effective anti-tumor immune response.
Publications (Second Author):
JG. Lyon, SL. Carroll, N. Mokarram, RV. Bellamkonda. Electrotaxis of Glioblastoma and Medulloblastoma Spheroidal Aggregates. Scientific Reports. (2019). PMC6441013
JD. Falcone, SL. Carroll, et al. Correlation of mRNA expression and signal variability in chronic intracortical electrodes. Frontiers in Bioengineering and Biotechnology (2018). PMC5880884