Aravind Asokan

Image of Aravind Asokan

Professor in Surgery

Synthetic Virology & Gene Therapy

Appointments and Affiliations

  • Professor in Surgery
  • Director of Gene Therapy
  • Professor of Molecular Genetics and Microbiology
  • Affiliate of the Regeneration Next Initiative

Contact Information:

Education:

  • Ph.D. University of North Carolina - Chapel Hill, 2004

Research Interests:

Virology
RNA Biology
Viral Engineering
RNA Engineering
Gene Therapy
Gene Editing
Gene Regulation
Regenerative Medicine

Courses Taught:

  • MGM 293: Research Independent Study I
  • MGM 593: Research Independent Study

Representative Publications:

  • Kang, MH; Hu, J; Pratt, RE; Hodgkinson, CP; Asokan, A; Dzau, VJ, Optimizing delivery for efficient cardiac reprogramming., Biochemical and Biophysical Research Communications (2020) [10.1016/j.bbrc.2020.08.104] [abs].
  • Das, A; Barrientos, R; Shiota, T; Madigan, V; Misumi, I; McKnight, KL; Sun, L; Li, Z; Meganck, RM; Li, Y; Kaluzna, E; Asokan, A; Whitmire, JK; Kapustina, M; Zhang, Q; Lemon, SM, Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus., Nature Microbiology, vol 5 no. 9 (2020), pp. 1069-1078 [10.1038/s41564-020-0727-8] [abs].
  • Madigan, VJ; Berry, GE; Tyson, TO; Nardone-White, D; Ark, J; Elmore, ZC; Murlidharan, G; Vincent, HA; Asokan, A, The Golgi calcium ATPase pump plays an essential role in AAV trafficking and transduction., J Virol (2020) [10.1128/JVI.01604-20] [abs].
  • Li, J; Li, Y; Wang, J; Gonzalez, TJ; Asokan, A; Napierala, JS; Napierala, M, Defining Transcription Regulatory Elements in the Human Frataxin Gene: Implications for Gene Therapy., Hum Gene Ther, vol 31 no. 15-16 (2020), pp. 839-851 [10.1089/hum.2020.053] [abs].
  • Havlik, LP; Simon, KE; Smith, JK; Klinc, KA; Tse, LV; Oh, DK; Fanous, MM; Meganck, RM; Mietzsch, M; Agbandje-McKenna, M; Asokan, A, Co-evolution of AAV capsid antigenicity and tropism through a structure-guided approach., J Virol (2020) [10.1128/JVI.00976-20] [abs].