BioE Seminar Series: Raluca Gordan, PhD
Thursday, October 28, 2021
12:00 pm - 1:00 pm
Raluca Gordan, PhD, Associate Professor, Departments of Biostatistics & Bioinformatics and Computer Science, Duke University
We develop quantitative computational and experimental approaches to identify and characterize transcriptional regulatory regions in the human genome. We combine machine learning techniques and high-throughput assays. Focusing on transcription factors (TFs) that control cell proliferation and differentiation, our goals are to understand: (1) how these regulatory proteins interact with each other to select their unique targets across the genome, and (2) how this regulation is disrupted in diseased cells due to non-coding mutations and TF overexpression.